CoQ10 improves erectile functionSafety and efficacy of coenzyme Q10 supplementation in early chronic Peyronie's disease: a double-blind, placebo-controlled randomized study.
High relevance to erectile dysfunction
We conducted a randomized, double-blind, placebo-controlled study to investigate the effectiveness of coenzyme Q10 (CoQ10) in treating erectile dysfunction (ED) in men diagnosed with early chronic Peyronie's disease (PD). A total of 186 participants took part, with half receiving 300 mg of CoQ10 daily and the other half receiving a placebo over a 24-week period.
Throughout the study, we regularly assessed various factors such as erectile function, pain during erection, plaque volume, and penile curvature. We also used a patient satisfaction questionnaire to gauge overall treatment satisfaction.
After 24 weeks, we observed significant improvements in erectile function and reduced pain for those taking CoQ10. Specifically, the CoQ10 group showed a notable increase in mean erectile function scores and a decrease in plaque size and penile curvature. In contrast, patients in the placebo group experienced disease progression more frequently.
Overall, our study suggests that CoQ10 supplements may effectively reduce symptoms related to ED in men suffering from Peyronie's disease. This potential advancement could offer hope for those still seeking effective treatments for this condition.
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CoQ10 shows limited efficacy in EDThe Role and Efficacy of Coenzyme Q10 in the Management of Erectile Dysfunction in a Hypertensive Male: An Interventional Study.
Study indicates limited isolated effect
We conducted a study to explore the effectiveness of Coenzyme Q10, or CoQ10, in treating erectile dysfunction (ED) among hypertensive men. This was a well-structured interventional study where we examined 230 hypertensive male patients. They were randomly divided into two groups—one received daily CoQ10 along with their regular antihypertensive medications, while the other group continued with their antihypertensive therapy alone.
Over three months, we assessed the erectile function of participants using the International Index of Erectile Function Test (IIEF-5). In our analysis of the findings, we noted that while overall improvements in erectile function were observed, the difference between the CoQ10 group and the control group was not statistically significant. Specifically, only about 20% of the participants in the CoQ10 group reported improvement after three months, indicating some potential benefit for men experiencing mild ED.
It's essential to mention that while we saw some gains in erectile function, particularly in a subgroup of men with mild ED, the overall impact of CoQ10 when combined with other treatments didn’t demonstrate a significant advantage. Thus, while CoQ10 may offer some hope for those with mild forms of ED, we conclude that the treatment alone may not be sufficient for all hypertensive patients suffering from this condition.
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